HMM Summary Page: TIGR00417

Functionspermidine synthase
Gene SymbolspeE
Trusted Cutoff249.55
Domain Trusted Cutoff249.55
Noise Cutoff147.40
Domain Noise Cutoff147.40
Isology Typeequivalog
EC Number2.5.1.16
HMM Length271
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryPolyamine biosynthesis
Gene Ontology TermGO:0004766: spermidine synthase activity molecular_function
GO:0008295: spermidine biosynthetic process biological_process
AuthorLoftus BJ
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
Commentthe SpeE subunit of spermidine synthase catalysesthe reaction (putrescine + S-adenosylmethioninamine = spermidine + 5'-methylthioadenosine) and is involved in polyamine biosynthesis and in the biosynthesis of spermidine from arganine. The region between residues 77 and 120 of the seed alignment is thought to be involved in binding to decarboxylated SAM.
ReferencesDR Swissprot; P09158; DR ECOCYC; EG10963; DR Swissprot; Q64674; SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_00198; 78 of 119
Genome PropertyGenProp0641: spermidine biosynthesis from putrescine and S-adenosylmethionine (HMM)