| Accession | TIGR00408 |
| Name | proS_fam_I |
| Function | proline--tRNA ligase |
| Gene Symbol | proS |
| Trusted Cutoff | 437.00 |
| Domain Trusted Cutoff | 437.00 |
| Noise Cutoff | 251.35 |
| Domain Noise Cutoff | 251.35 |
| Isology Type | equivalog |
| EC Number | 6.1.1.15 |
| HMM Length | 475 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA aminoacylation |
| Gene Ontology Term | GO:0004827: proline-tRNA ligase activity molecular_function |
| | GO:0006433: prolyl-tRNA aminoacylation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Prolyl-tRNA synthetase is a class II tRNA synthetase and is recognized by pfam HMM tRNA-synt_2b, which recognizes tRNA synthetases for Gly, His, Ser, and Pro. The prolyl-tRNA synthetases are divided into two widely divergent families. This family includes the archaeal enzyme, the Pro-specific domain of a human multifunctional tRNA ligase, and the enzyme from the spirochete Borrelia burgdorferi. The other family includes enzymes from Escherichia coli, Bacillus subtilis, Synechocystis PCC6803, and one of the two prolyL-tRNA synthetases of Saccharomyces cerevisiae. |
| References | SE TIGR
GA hmmls
DR HAMAP; MF_01571; 112 of 114 |
| Genome Property | GenProp0258: tRNA aminoacylation (HMM) |
| | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
| | GenProp0831: archaeal core gene set, exactly 1 per genome (HMM) |
