HMM Summary Page: TIGR00407

Functionglutamate-5-semialdehyde dehydrogenase
Gene SymbolproA
Trusted Cutoff317.45
Domain Trusted Cutoff317.45
Noise Cutoff240.45
Domain Noise Cutoff240.45
Isology Typeequivalog_domain
EC Number1.2.1.41
HMM Length398
Mainrole CategoryAmino acid biosynthesis
Subrole CategoryGlutamate family
Gene Ontology TermGO:0004350: glutamate-5-semialdehyde dehydrogenase activity molecular_function
GO:0006561: proline biosynthetic process biological_process
AuthorLoftus BJ
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe related HMM TIGR01092 describes a full-length fusion protein delta l-pyrroline-5-carboxylate synthetase that includes a gamma-glutamyl phosphate reductase region as described by this model. Alternate name: glutamate-5-semialdehyde dehydrogenase. The prosite motif begins at residue 332 of the seed alignment although not all of the members of the family exactly obey the motif.
ReferencesDR Swissprot; P07004; DR ECOCYC; EG10767; DR PROSITE; PDOC00940 DR PFAM; PF00696; SE TIGR DR HAMAP; MF_00412; 394 of 405
Genome PropertyGenProp0111: proline biosynthesis from glutamate (HMM)