| Accession | TIGR00396 |
| Name | leuS_bact |
| Function | leucine--tRNA ligase |
| Gene Symbol | leuS |
| Trusted Cutoff | 548.40 |
| Domain Trusted Cutoff | 548.40 |
| Noise Cutoff | 335.30 |
| Domain Noise Cutoff | 335.30 |
| Isology Type | equivalog |
| EC Number | 6.1.1.4 |
| HMM Length | 843 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA aminoacylation |
| Gene Ontology Term | GO:0004823: leucine-tRNA ligase activity molecular_function |
| | GO:0005737: cytoplasm cellular_component |
| | GO:0006429: leucyl-tRNA aminoacylation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | The leucyl-tRNA synthetases belong to two families so broadly different that they are represented by separate models. This model includes both eubacterial and mitochondrial leucyl-tRNA synthetases. It generates higher scores for some valyl-tRNA synthetases than for any archaeal or eukaryotic cytosolic leucyl-tRNA synthetase. Note that the enzyme from Aquifex aeolicus is split into alpha and beta chains; neither chain is long enough to score above the trusted cutoff, but the alpha chain scores well above the noise cutoff. The beta chain must be found by a model and search designed for partial length matches. |
| References | SE TIGR
GA hmmls
AL clustalw, seaview, belvu
DR HAMAP; MF_00049; 507 of 550 |
| Genome Property | GenProp0258: tRNA aminoacylation (HMM) |
| | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
