HMM Summary Page: TIGR00394

FunctionPTS system, lactose-specific IIC component
Trusted Cutoff614.40
Domain Trusted Cutoff614.40
Noise Cutoff388.15
Domain Noise Cutoff388.15
Isology Typeequivalog_domain
EC Number2.7.1.69
HMM Length412
Mainrole CategoryTransport and binding proteins
Subrole CategoryCarbohydrates, organic alcohols, and acids
Gene Ontology TermGO:0009401: phosphoenolpyruvate-dependent sugar phosphotransferase system biological_process
GO:0015155: lactose transmembrane transporter activity molecular_function
GO:0019197: phosphoenolpyruvate-dependent sugar phosphotransferase complex cellular_component
AuthorLoftus BJ
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis family of proteins models the IIC domain of the phosphotransferase system (PTS) for lactose. The IIC domain catalyzes the transfer of a phosphoryl group from the IIB domain to lactose. When the IIC component and IIB components are in the same polypeptide chain they are designated IIBC.
ReferencesRM 93015655 RT Nucleotide and deduced amino acid sequences of the lacR, lacABCD, and lacFE genes encoding the repressor, tagatose 6-phosphate gene cluster, and sugar-specific phosphotransferase system components of the lactose operon of Streptococcus mutans. RA Rosey EL, Stewart GC RL J Bacteriol 1992 Oct;174(19):6159-70 DR SWISSPROT; P50976; SE TIGR GA hmmls BD 0487 DR PFAM; PF02378 DR InterPro; IPR003352 DR URL;
Genome PropertyGenProp0119: PTS transport system (HMM)