HMM Summary Page: TIGR00393

Functionsugar isomerase, KpsF/GutQ family
Trusted Cutoff203.70
Domain Trusted Cutoff203.70
Noise Cutoff137.15
Domain Noise Cutoff137.15
Isology Typesubfamily
HMM Length268
Mainrole CategoryEnergy metabolism
Subrole CategorySugars
Gene Ontology TermGO:0005975: carbohydrate metabolic process biological_process
GO:0016853: isomerase activity molecular_function
AuthorLoftus BJ
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM describes a number of closely related proteins with the phosphosugar-binding domain SIS (Sugar ISomerase) followed by two copies of the CBS (named after Cystathionine Beta Synthase) domain. One is GutQ, a protein of the glucitol operon. Another is KpsF, a virulence factor involved in capsular polysialic acid biosynthesis in some pathogenic strains of E. coli.
ReferencesDR PFAM; PF01380; SIS DR PFAM; PF00571; CBS; DR EGAD:89096, EGAD:20643 SE TIGR GA hmmls