HMM Summary Page: TIGR00380

Functioncobalamin biosynthesis protein CobD
Gene SymbolcobD
Trusted Cutoff165.90
Domain Trusted Cutoff165.90
Noise Cutoff148.20
Domain Noise Cutoff148.20
Isology Typeequivalog
EC Number6.3.1.10
HMM Length305
Mainrole CategoryBiosynthesis of cofactors, prosthetic groups, and carriers
Subrole CategoryHeme, porphyrin, and cobalamin
Gene Ontology TermGO:0009236: cobalamin biosynthetic process biological_process
GO:0016880: acid-ammonia (or amide) ligase activity molecular_function
AuthorLoftus BJ
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis protein is involved in cobalamin (vitamin B12) biosynthesis and porphyrin biosynthesis. It converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. It is part of the cob operon.
ReferencesRN [1] RM 96146525 RT Salmonella typhimurium cobalamin (vitamin B12) biosynthetic genes: functional studies in S. typhimurium and Escherichia coli. RN [2] RM 95362677 RT Identification and sequence analysis of genes involved in late steps in cobalamin (vitamin B12) synthesis in Rhodobacter capsulatus. DR SWISSPROT; Q05600; SE TIGR GA hmmls DR HAMAP; MF_00024; 47 of 48
Genome PropertyGenProp0269: coenzyme B12 biosynthesis from cob(II)yrinate diamide (HMM)