HMM Summary Page: TIGR00376

Functionputative DNA helicase
Trusted Cutoff348.90
Domain Trusted Cutoff348.90
Noise Cutoff276.05
Domain Noise Cutoff276.05
Isology Typehypoth_equivalog
EC Number3.6.4.12
HMM Length639
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0003678: DNA helicase activity molecular_function
GO:0006281: DNA repair biological_process
AuthorLoftus BJ
Entry DateApr 20 1999 2:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe gene product may represent a DNA helicase. Eukaryotic members of this family have been characterized as binding certain single-stranded G-rich DNA sequences (GGGGT and GGGCT). A number of related proteins are characterized as helicases.
ReferencesA2 hmmalign RM 93352537 RT The human S mu bp-2, a DNA-binding protein specific to the single-stranded guanine-rich sequence related to the immunoglobulin mu chain switch region. RA Fukita Y, Mizuta TR, Shirozu M, Ozawa K, Shimizu A, Honjo T RL Biol Chem 1993 Aug 15;268(23):17463-70 DR EGAD:44287, SP:Q57568, SE TIGR GA hmmls AL clustalw, belvu