HMM Summary Page: TIGR00373

Functiontranscription factor E
Gene Symboltfe
Trusted Cutoff149.50
Domain Trusted Cutoff149.50
Noise Cutoff61.70
Domain Noise Cutoff61.70
Isology Typeequivalog
HMM Length162
Mainrole CategoryHypothetical proteins
Subrole CategoryConserved
AuthorHaft DH, Loftus BJ
Entry DateApr 20 1999 2:05PM
Last ModifiedAug 12 2012 9:15PM
CommentThis family of proteins is, so far, restricted to archaeal genomes. The family appears to be distantly related to the N-terminal region of the eukaryotic transcription initiation factor IIE alpha chain.
ReferencesRN [1] RM PMID:13679366 RT An extended winged helix domain in general transcription factor E/IIE alpha. RA Meinhart A, Blobel J, Cramer P RL J Biol Chem. 2003 Nov 28;278(48):48267-74. RN [2] RM PMID:17921145 RT Transcription factor E is a part of transcription elongation complexes. RA Grunberg S, Bartlett MS, Naji S, Thomm M RL J Biol Chem. 2007 Dec 7;282(49):35482-90. DR HAMAP; MF_01909; 18 of 45