| Accession | TIGR00372 |
| Name | cas4 |
| Function | CRISPR-associated protein Cas4 |
| Gene Symbol | cas4 |
| Trusted Cutoff | 65.00 |
| Domain Trusted Cutoff | 65.00 |
| Noise Cutoff | 59.90 |
| Domain Noise Cutoff | 59.90 |
| Isology Type | equivalog |
| HMM Length | 180 |
| Mainrole Category | Mobile and extrachromosomal element functions |
| Subrole Category | Other |
| Gene Ontology Term | GO:0003674: molecular_function molecular_function |
| | GO:0043571: maintenance of CRISPR repeat elements biological_process |
| Author | Haft DH, Loftus BJ |
| Entry Date | Apr 20 1999 2:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This HMM represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p. |
| References | DR URL http://www.tigr.org/tigr-scripts/CMR2/genome_property_def.spl?prop=2003
RN [1]
RT A guild of 45 CRISPR-associated (Cas) protein families and multiple CRISPR/cas subtypes exist in prokaryotic genomes
RA Haft DH, Selengut JD, Mongodin EF, Nelsen KE
RL PLOS Comput. Biol. 1(6), e60-e69, 2005
RN [2]
RM 11952905
RT Identification of genes that are associated with DNA repeats in prokaryotes.
RA Jansen R, Embden JD, Gaastra W, Schouls LM.
RL Mol Microbiol 2002 Mar;43(6):1565-75
RN [3]
RM 11788711
RT A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis.
RA Makarova KS, Aravind L, Grishin NV, Rogozin IB, Koonin EV.
RL Nucleic Acids Res. 2002 Jan 15;30(2):482-96. |
| Genome Property | GenProp0021: CRISPR region (HMM) |
| | GenProp0313: CRISPR system, I-C/Dvulg subtype (HMM-CLUST) |
| | GenProp0317: CRISPR system, I-B subtype, Tneap branch (HMM-CLUST) |
| | GenProp0319: CRISPR system, I-A/Apern subtype (HMM-CLUST) |
| | GenProp0320: CRISPR system, I-B subtype, Hmari branch (HMM-CLUST) |
| | GenProp0469: CRISPR system, Dpsyc subtype (HMM-CLUST) |
| | GenProp0768: CRISPR system, Pging subtype (HMM-CLUST) |
| | GenProp0922: CRISPR system, Myxan subtype (HMM-CLUST) |
