HMM Summary Page: TIGR00362

Functionchromosomal replication initiator protein DnaA
Gene SymboldnaA
Trusted Cutoff343.90
Domain Trusted Cutoff343.90
Noise Cutoff184.65
Domain Noise Cutoff184.65
Isology Typeequivalog
HMM Length437
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
Gene Ontology TermGO:0003677: DNA binding molecular_function
GO:0003688: DNA replication origin binding molecular_function
GO:0005524: ATP binding molecular_function
GO:0006270: DNA-dependent DNA replication initiation biological_process
GO:0006275: regulation of DNA replication biological_process
AuthorLoftus BJ, Haft DH
Entry DateApr 20 1999 2:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentDnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006).
ReferencesRN [1] RM PMID:16753031 RT DnaA: controlling the initiation of bacterial DNA replication and more. RA Kaguni JM RL Annu Rev Microbiol. 2006;60:351-75. DR PFAM; PF00308; bac_dnaA; DR PROSITE; PDOC00771; DR ECOCYC; EG10235; dnaA; DR SWISSPROT; P03004; SE TIGR DR HAMAP; MF_00377; 410 of 419
Genome PropertyGenProp0799: bacterial core gene set, exactly 1 per genome (HMM)
GenProp0806: replication initiation, bacterial (HMM)