HMM Summary Page: TIGR00361

FunctionDNA internalization-related competence protein ComEC/Rec2
Trusted Cutoff190.05
Domain Trusted Cutoff190.05
Noise Cutoff164.20
Domain Noise Cutoff164.20
Isology Typeequivalog
HMM Length663
Mainrole CategoryCellular processes
Subrole CategoryDNA transformation
Gene Ontology TermGO:0005215: transporter activity molecular_function
GO:0009290: DNA import into cell involved in transformation biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentApparant orthologs are found in 5 species so far (Haemophilus influenzae, Escherichia coli, Bacillus subtilis, Neisseria gonorrhoeae, Streptococcus pneumoniae), of which all but E. coli are model systems for the study of competence for natural transformation. This protein is a predicted multiple membrane-spanning protein likely to be involved in DNA internalization. In a large number of bacterial species not known to exhibit competence, this protein is replaced by a half-length N-terminal homolog of unknown function, modelled by the related HMM ComEC_N-term. The role for this protein in species that are not naturally transformable is unknown.
ReferencesSE TIGR GA hmmls
Genome PropertyGenProp0311: competence-related genes (HMM)