| Accession | TIGR00355 |
| Name | purH |
| Function | phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase |
| Gene Symbol | purH |
| Trusted Cutoff | 528.00 |
| Domain Trusted Cutoff | 528.00 |
| Noise Cutoff | 462.65 |
| Domain Noise Cutoff | 462.65 |
| Isology Type | equivalog |
| EC Number | 2.1.2.3 3.5.4.10 |
| HMM Length | 511 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Purine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0003937: IMP cyclohydrolase activity molecular_function |
| | GO:0004643: phosphoribosylaminoimidazolecarboxamide formyltransferase activity molecular_function |
| | GO:0009152: purine ribonucleotide biosynthetic process biological_process |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | PurH is bifunctional: IMP cyclohydrolase (EC 3.5.4.10); phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3)
Involved in purine ribonucleotide biosynthesis. The IMP cyclohydrolase activity is in the N-terminal region. |
| References | DR ECOCYC; EG10795; purH;
DR SWISSPROT; P15639;
SE TIGR
GA hmmls
AL clustalw, belvu
DR HAMAP; MF_00139; 305 of 310 |
| Genome Property | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
| | GenProp0110: purine (inosine-5'-phosphate) biosynthesis from ribose-5-phosphate (HMM) |
