HMM Summary Page: TIGR00346

Functionazaleucine resistance protein AzlC
Gene SymbolazlC
Trusted Cutoff332.35
Domain Trusted Cutoff332.35
Noise Cutoff49.70
Domain Noise Cutoff49.70
Isology Typeequivalog
HMM Length221
Mainrole CategoryTransport and binding proteins
Subrole CategoryAmino acids, peptides and amines
Gene Ontology TermGO:0006865: amino acid transport biological_process
GO:0015171: amino acid transmembrane transporter activity molecular_function
AuthorLoftus BJ
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentOverexpression of this gene results in resistance to a leucine analog, 4-azaleucine. The protein has 5 potential transmembrane motifs. It has been inferred, but not experimentally demonstrated, to be part of a branched-chain amino acid transport system. Commonly found in association with azlD.
ReferencesRM 97431495 RT An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport. RA Belitsky BR, Gustafsson MC, Sonenshein AL, Von Wachenfeldt C RL J Bacteriol 1997 Sep;179(17):5448-57 SE TIGR DR URL;