| Accession | TIGR00337 |
| Name | PyrG |
| Function | CTP synthase |
| Gene Symbol | pyrG |
| Trusted Cutoff | 462.75 |
| Domain Trusted Cutoff | 462.75 |
| Noise Cutoff | 289.55 |
| Domain Noise Cutoff | 289.55 |
| Isology Type | equivalog |
| EC Number | 6.3.4.2 |
| HMM Length | 526 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Pyrimidine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0003883: CTP synthase activity molecular_function |
| | GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:04PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | CTP synthase is involved in pyrimidine ribonucleotide/ribonucleoside metabolism. The enzyme catalyzes the reaction L-glutamine + H2O + UTP + ATP = CTP + phosphate + ADP + L-glutamate. The enzyme exists as a dimer of identical chains that aggregates as a tetramer. This gene has been found circa 500 bp 5' upstream of enolase in both beta (Nitrosomonas europaea) and gamma (E.coli) subdivisions of proteobacterium (FEMS Microbiol Lett 1998 Aug 1;165(1):153-7). |
| References | DR ECOCYC; EG10810; pyrG;
DR PROSITE; PDOC00405;
SE TIGR
GA hmmls
DR HAMAP; MF_01227; 345 of 347 |
| Genome Property | GenProp0799: bacterial core gene set, exactly 1 per genome (HMM) |
