HMM Summary Page: TIGR00333

FunctionnrdI protein
Gene SymbolnrdI
Trusted Cutoff74.65
Domain Trusted Cutoff74.65
Noise Cutoff53.60
Domain Noise Cutoff53.60
Isology Typeequivalog
HMM Length127
Mainrole CategoryPurines, pyrimidines, nucleosides, and nucleotides
Subrole Category2'-Deoxyribonucleotide metabolism
Gene Ontology TermGO:0009263: deoxyribonucleotide biosynthetic process biological_process
AuthorLoftus BJ
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentRibonucleotide reductases (RNRs) are enzymes that provide the precursors of DNA synthesis. The three characterized classes of RNRs differ by their metal cofactor and their stable organic radical. The exact function of nrdI within the ribonucleotide reductases has not yet been fully characterised.
ReferencesDR ECOCYC; EG13287; nrdI RM 98136125 RT The manganese-containing ribonucleotide reductase of Corynebacterium ammoniagenes is a class Ib enzyme. RA Fieschi F, Torrents E, Toulokhonova L, Jordan A, Hellman U, Barbe J, Gibert I, Karlsson M, Sjoberg BM RL J Biol Chem 1998 Feb 20;273(8):4329-37 SE TIGR GA hmmls AL clustalw DR HAMAP; MF_00128; 109 of 110
Genome PropertyGenProp0289: class I (aerobic) ribonucleotide reductase (HMM)