| Accession | TIGR00325 |
| Name | lpxC |
| Function | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase |
| Gene Symbol | lpxC |
| Trusted Cutoff | 187.25 |
| Domain Trusted Cutoff | 187.25 |
| Noise Cutoff | 155.00 |
| Domain Noise Cutoff | 155.00 |
| Isology Type | equivalog |
| EC Number | 3.5.1.- |
| HMM Length | 297 |
| Mainrole Category | Cell envelope |
| Subrole Category | Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides |
| Gene Ontology Term | GO:0008759: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity molecular_function |
| | GO:0009245: lipid A biosynthetic process biological_process |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc deacetylase from E. coli , LpxC, was previously designated EnvA. This enzyme is involved in lipid-A precursor biosynthesis. It is essential for cell viability. |
| References | SE TIGR
AL clustalw
DR ECOCYC; EG10265; lpxC
DR SWISSPROT; P07652
GA hmmls
RN [1]
RM 99152380
RT UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase of Escherichia coli is a zinc metalloenzyme.
RA Jackman JE, Raetz CR, Fierke CA
RL Biochemistry 1999 Feb 9;38(6):1902-11
DR HAMAP; MF_00388; 197 of 201 |
| Genome Property | GenProp0204: KDO(2)-lipid A (Re LPS) biosynthesis and delivery (HMM) |
