HMM Summary Page: TIGR00314

FunctionCO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit
Gene SymbolcdhA
Trusted Cutoff781.30
Domain Trusted Cutoff781.30
Noise Cutoff384.00
Domain Noise Cutoff384.00
Isology Typeequivalog
EC Number1.2.99.2
HMM Length784
Mainrole CategoryEnergy metabolism
Subrole CategoryChemoautotrophy
Gene Ontology TermGO:0006085: acetyl-CoA biosynthetic process biological_process
GO:0018492: carbon-monoxide dehydrogenase (acceptor) activity molecular_function
AuthorLoftus BJ
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentAcetyl-CoA decarbonylase/synthase (ACDS) is a multienzyme complex. Carbon monoxide dehydrogenase is a synonym. The ACDS complex carries out an unusual reaction involving the reversible cleavage and synthesis of acetyl-CoA in methanogens. The model contains the prosite signature for 4Fe-4S ferredoxins [C-x(2)-C-x(2)-C-x(3)-C-[PEG]] between residues 448-462 of the model.
ReferencesDR PROSITE; PDOC00176; 4FE4S_FERREDOXIN SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_01137; 13 of 13