| Accession | TIGR00308 |
| Name | TRM1 |
| Function | N2,N2-dimethylguanosine tRNA methyltransferase |
| Trusted Cutoff | 280.65 |
| Domain Trusted Cutoff | 280.65 |
| Noise Cutoff | 153.90 |
| Domain Noise Cutoff | 153.90 |
| Isology Type | equivalog |
| EC Number | 2.1.1.- |
| HMM Length | 375 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0004809: tRNA (guanine-N2-)-methyltransferase activity molecular_function |
| | GO:0030488: tRNA methylation biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This enzyme is responsible for two methylations of a characteristic guanine of most tRNA molecules. The activity has been demonstrated for eukaryotic and archaeal proteins, which are active when expressed in E. coli, a species that lacks this enzyme. At least one Eubacterium, Aquifex aeolicus, has an ortholog, as do all completed archaeal genomes. |
| References | SE TIGR
GA hmmls
AL clustalw, belvu, seaview
DR HAMAP; MF_00290; 21 of 26 |
