Accession | TIGR00308 |
Name | TRM1 |
Function | N2,N2-dimethylguanosine tRNA methyltransferase |
Trusted Cutoff | 280.65 |
Domain Trusted Cutoff | 280.65 |
Noise Cutoff | 153.90 |
Domain Noise Cutoff | 153.90 |
Isology Type | equivalog |
EC Number | 2.1.1.- |
HMM Length | 375 |
Mainrole Category | Protein synthesis |
Subrole Category | tRNA and rRNA base modification |
Gene Ontology Term | GO:0004809: tRNA (guanine-N2-)-methyltransferase activity molecular_function |
| GO:0030488: tRNA methylation biological_process |
Author | Haft DH |
Entry Date | Apr 20 1999 2:06PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This enzyme is responsible for two methylations of a characteristic guanine of most tRNA molecules. The activity has been demonstrated for eukaryotic and archaeal proteins, which are active when expressed in E. coli, a species that lacks this enzyme. At least one Eubacterium, Aquifex aeolicus, has an ortholog, as do all completed archaeal genomes. |
References | SE TIGR
GA hmmls
AL clustalw, belvu, seaview
DR HAMAP; MF_00290; 21 of 26 |