HMM Summary Page: TIGR00306

Functionphosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form
Gene SymbolapgM
Trusted Cutoff264.50
Domain Trusted Cutoff264.50
Noise Cutoff95.50
Domain Noise Cutoff95.50
Isology Typesubfamily
EC Number5.4.2.12
HMM Length396
Mainrole CategoryEnergy metabolism
Subrole CategoryGlycolysis/gluconeogenesis
Gene Ontology TermGO:0006094: gluconeogenesis biological_process
GO:0006096: glycolysis biological_process
GO:0046537: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity molecular_function
AuthorLoftus BJ, Haft DH, Dodson RJ
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentExperimentally characterized in archaea as 2,3-bisphosphoglycerate-independent phosphoglycerate mutase. This model describes a set of proteins in the Archaea (two each in Methanococcus jannaschii, Methanobacterium thermoautotrophicum, and Archaeoglobus fulgidus) and in Aquifex aeolicus (1 member).
References[1] RM 12062435 RT A divergent archaeal member of the alkaline phosphatase binuclear metalloenzyme superfamily has phosphoglycerate mutase activity. RL FEBS Lett. 2002 Apr 24;517(1-3):190-4. RA Graham DE, Xu H, White RH. [2] RM 12076796 RT Molecular characterization of phosphoglycerate mutase in archaea. RL FEMS Microbiol Lett. 2002 Jun 18;212(1):111-20. RA van der Oost J, Huynen MA, Verhees CH. RM 97272486 SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_01402; 45 of 47
Genome PropertyGenProp0691: glycolysis (HMM)