| Accession | TIGR00298 |
| Name | TIGR00298 |
| Function | 2-phosphosulfolactate phosphatase |
| Gene Symbol | comB |
| Trusted Cutoff | 175.05 |
| Domain Trusted Cutoff | 175.05 |
| Noise Cutoff | 119.70 |
| Domain Noise Cutoff | 119.70 |
| Isology Type | equivalog |
| EC Number | 3.1.3.71 |
| HMM Length | 216 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0019295: coenzyme M biosynthetic process biological_process |
| | GO:0050532: 2-phosphosulfolactate phosphatase activity molecular_function |
| Author | Haft DH, Dodson RJ |
| Entry Date | Apr 20 1999 2:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | 2-phosphosulfolactate phosphatase catalyzes the sulfonation of phosphoenolpyruvate to form 2-phospho-3-sulfolactate, the second step in coenzyme M biosynthesis. Coenzyme M is the terminal methyl carrier in methanogenesis. |
| References | [1]
RM 11589710
RT Identification of coenzyme M biosynthetic 2-phosphosulfolactate phosphatase. A member of a new class of Mg(2+)-dependent acid phosphatases.
RL Eur J Biochem. 2001 Oct;268(19):5176-88.
RA Graham DE, Graupner M, Xu H, White RH.
SE TIGR
GA hmmls
AL clustalw, belvu
DR HAMAP; MF_00490; 27 of 46 |
| Genome Property | GenProp0892: sulfopyruvate biosynthesis from phoshoenolpyruvate (HMM) |
