HMM Summary Page: TIGR00286

Functionarginine decarboxylase, pyruvoyl-dependent
Trusted Cutoff106.95
Domain Trusted Cutoff106.95
Noise Cutoff43.50
Domain Noise Cutoff43.50
Isology Typeequivalog
EC Number4.1.1.19
HMM Length152
Mainrole CategoryCentral intermediary metabolism
Subrole CategoryPolyamine biosynthesis
Gene Ontology TermGO:0006527: arginine catabolic process biological_process
GO:0006596: polyamine biosynthetic process biological_process
GO:0008792: arginine decarboxylase activity molecular_function
AuthorHaft DH
Entry DateApr 20 1999 2:05PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe three copies present in Archeoglobus fulgidus, one of which is only half-length and excluded from the seed alignment, are very closely related and clearly arose by duplication after the separation from well-studied species. The other completed archaeal genomes each contain a single copy. The lone, weak (below trusted cutoff) hit to a non-archaeal sequence is to an uncharacterized protein of Chlamydia, with the greatest similarity in the amino-terminal half of the model.
ReferencesRM 11980912 RT Methanococcus jannaschii uses a pyruvoyl-dependent arginine decarboxylase in polyamine biosynthesis. RA Graham DE, Xu H, White RH. RL J Biol Chem. 2002 Jun 28;277(26):23500-7. SE TIGR DR HAMAP; MF_01404; 25 of 27