| Accession | TIGR00263 |
| Name | trpB |
| Function | tryptophan synthase, beta subunit |
| Gene Symbol | trpB |
| Trusted Cutoff | 392.45 |
| Domain Trusted Cutoff | 392.45 |
| Noise Cutoff | 220.75 |
| Domain Noise Cutoff | 220.75 |
| Isology Type | equivalog |
| EC Number | 4.2.1.20 |
| HMM Length | 385 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Aromatic amino acid family |
| Gene Ontology Term | GO:0000162: tryptophan biosynthetic process biological_process |
| | GO:0004834: tryptophan synthase activity molecular_function |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Tryptophan synthase catalyzes the last step in the biosynthesis of tryptophan. the beta chain contains the functional domain for or the synthesis of tryptophan from indole and serine. The enzyme requires pyridoxal-phosphate as a cofactor. The pyridoxal-P attachment site is contained within the conserved region [LIVM]-x-H-x-G-[STA]-H-K-x-N] [K is the pyridoxal-P attachment site] which is present between residues 90-100 of the model. |
| References | DR Swissprot; P00932;
DR ECOCYC; EG11025;
DR PROSITE; PS00168;
SE TIGR
GA hmmls
DR HAMAP; MF_00133; 288 of 315 |
| Genome Property | GenProp0037: tryptophan biosynthesis from ribose-5-phosphate (HMM) |
