| Accession | TIGR00243 |
| Name | Dxr |
| Function | 1-deoxy-D-xylulose 5-phosphate reductoisomerase |
| Gene Symbol | dxr |
| Trusted Cutoff | 315.70 |
| Domain Trusted Cutoff | 315.70 |
| Noise Cutoff | 224.55 |
| Domain Noise Cutoff | 224.55 |
| Isology Type | equivalog |
| EC Number | 1.1.1.267 |
| HMM Length | 389 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0005737: cytoplasm cellular_component |
| | GO:0019288: isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway biological_process |
| | GO:0030604: 1-deoxy-D-xylulose-5-phosphate reductoisomerase activity molecular_function |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:03PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | 1-deoxy-D-xylulose 5-phosphate is converted to 2-C-methyl-D-erythritol 4-phosphate in the presence of NADPH. It is involved in the synthesis of isopentenyl diphosphate (IPP), a basic building block in isoprenoid, thiamin, and pyridoxal biosynthesis. |
| References | RL Proc Natl Acad Sci U S A 1998 Aug 18;95(17):9879-84
SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_00183; 297 of 301 |
| Genome Property | GenProp0048: IPP biosynthesis via deoxyxylulose (HMM) |
