HMM Summary Page: TIGR00241

Functionputative CoA-substrate-specific enzyme activase
Trusted Cutoff125.40
Domain Trusted Cutoff125.40
Noise Cutoff107.95
Domain Noise Cutoff107.95
Isology Typedomain
HMM Length248
Gene Ontology TermGO:0008047: enzyme activator activity molecular_function
GO:0018307: enzyme active site formation biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:03PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis domain is found in a set of closely related proteins including the (R)-2-hydroxyglutaryl-CoA dehydratase activase of Acidaminococcus fermentans, in longer proteins from M. jannaschii and M. thermoautotrophicum that share an additional N-terminal domain, in a protein described as a subunit of the benzoyl-CoA reductase of Rhodopseudomonas palustris, and in two repeats of an uncharacterized protein of Aquifex aeolicus. This domain may be involved in generating or regenerating the active sites of enzymes related to (R)-2-hydroxyglutaryl-CoA dehydratase and benzoyl-CoA reductase.
ReferencesA2 hmmalign SE TIGR GA hmmls AL clustalw BD 0342