| Accession | TIGR00240 |
| Name | ATCase_reg |
| Function | aspartate carbamoyltransferase, regulatory subunit |
| Gene Symbol | pyrI |
| Trusted Cutoff | 148.55 |
| Domain Trusted Cutoff | 148.55 |
| Noise Cutoff | 68.10 |
| Domain Noise Cutoff | 68.10 |
| Isology Type | equivalog |
| EC Number | 2.1.3.2 |
| HMM Length | 150 |
| Mainrole Category | Purines, pyrimidines, nucleosides, and nucleotides |
| Subrole Category | Pyrimidine ribonucleotide biosynthesis |
| Gene Ontology Term | GO:0004070: aspartate carbamoyltransferase activity molecular_function |
| | GO:0009220: pyrimidine ribonucleotide biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:03PM |
| Last Modified | May 25 2011 6:04PM |
| Comment | The presence of this regulatory subunit allows feedback inhibition by CTP on aspartate carbamoyltransferase, the first step in the synthesis of CTP from aspartate. In many species, this regulatory subunit is not present. In Thermotoga maritima, the catalytic and regulatory subunits are encoded by a fused gene and the regulatory region has enough sequence differences to score below the trusted cutoff. |
| References | DR EC 2.1.3.2
SE TIGR
GA hmmls
AL clustalw, belvu
DR HAMAP; MF_00002; 109 of 115 |
| Genome Property | GenProp0187: pyrimidine (uridine-5'-phosphate) de novo biosynthesis (HMM) |
