| Accession | TIGR00237 |
| Name | xseA |
| Function | exodeoxyribonuclease VII, large subunit |
| Gene Symbol | xseA |
| Trusted Cutoff | 180.00 |
| Domain Trusted Cutoff | 180.00 |
| Noise Cutoff | 100.00 |
| Domain Noise Cutoff | 100.00 |
| Isology Type | equivalog |
| EC Number | 3.1.11.6 |
| HMM Length | 389 |
| Mainrole Category | DNA metabolism |
| Subrole Category | Degradation of DNA |
| Gene Ontology Term | GO:0006308: DNA catabolic process biological_process |
| | GO:0008855: exodeoxyribonuclease VII activity molecular_function |
| | GO:0009318: exodeoxyribonuclease VII complex cellular_component |
| Author | Loftus BJ, Haft DH |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | May 27 2014 6:46PM |
| Comment | This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. |
| References | DR ECOCYC; EG11072;
RN [1]
RM PMID:22718974
RT Delineation of structural domains and identification of functionally important residues in DNA repair enzyme exonuclease VII.
RA Poleszak K, Kaminska KH, Dunin-Horkawicz S, Lupas A, Skowronek KJ, Bujnicki JM
RL Nucleic Acids Res. 2012 Sep;40(16):8163-74. doi: 10.1093/nar/gks547.
RN [2]
RM PMID:6284744
RT Subunit structure of Escherichia coli exonuclease VII.
RA Vales LD, Rabin BA, Chase JW.
RL J Biol Chem. 1982 Aug 10;257(15):8799-805.
DR HAMAP; MF_00378; 288 of 293 |
| Genome Property | GenProp1095: exodeoxyribonuclease VII (HMM) |
