HMM Summary Page: TIGR00234

Functiontyrosine--tRNA ligase
Gene SymboltyrS
Trusted Cutoff113.80
Domain Trusted Cutoff113.80
Noise Cutoff82.25
Domain Noise Cutoff82.25
Isology Typeequivalog
EC Number6.1.1.1
HMM Length406
Mainrole CategoryProtein synthesis
Subrole CategorytRNA aminoacylation
Gene Ontology TermGO:0004831: tyrosine-tRNA ligase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006437: tyrosyl-tRNA aminoacylation biological_process
AuthorLoftus BJ
Entry DateApr 20 1999 2:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis tyrosyl-tRNA synthetase model starts picking up tryptophanyl-tRNA synthetases at scores of 0 and below. The proteins found by this model have a deep split between two groups. One group contains bacterial and organellar eukaryotic examples. The other contains archaeal and cytosolic eukaryotic examples.
ReferencesDR PFAM; PF00579; tRNA-synt_1b; DR PROSITE; PDOC00161; Aminoacyl-transfer RNA synthetases class-I signature SE TIGR GA hmmls AL clustalw, belvu DR HAMAP; MF_02009; 15 of 17
Genome PropertyGenProp0258: tRNA aminoacylation (HMM)
GenProp0799: bacterial core gene set, exactly 1 per genome (HMM)
GenProp0832: archaeal core gene set, 1 or more per genome (HMM)