Accession | TIGR00232 |
Name | tktlase_bact |
Function | transketolase |
Gene Symbol | tkt |
Trusted Cutoff | 682.25 |
Domain Trusted Cutoff | 682.25 |
Noise Cutoff | 621.15 |
Domain Noise Cutoff | 621.15 |
Isology Type | equivalog |
EC Number | 2.2.1.1 |
HMM Length | 654 |
Mainrole Category | Energy metabolism |
Subrole Category | Pentose phosphate pathway |
Gene Ontology Term | GO:0004802: transketolase activity molecular_function |
| GO:0005737: cytoplasm cellular_component |
| GO:0006098: pentose-phosphate shunt biological_process |
Author | Haft DH, Richardson DL |
Entry Date | Apr 20 1999 2:10PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | This HMM is designed to capture orthologs of bacterial transketolases. The group includes two from the yeast Saccharomyces cerevisiae but excludes dihydroxyactetone synthases (formaldehyde transketolases) from various yeasts and the even more distant mammalian transketolases. Among the family of thiamine diphosphate-dependent enzymes that includes transketolases, dihydroxyacetone synthases, pyruvate dehydrogenase E1-beta subunits, and deoxyxylulose-5-phosphate synthases, mammalian and bacterial transketolases seem not to be orthologous. |
References | A2 hmmalign
SE TIGR
GA hmmls
AL clustalw
BD 0271 |
Genome Property | GenProp0120: pentose phosphate cycle (HMM) |