HMM Summary Page: TIGR00232

Gene Symboltkt
Trusted Cutoff682.25
Domain Trusted Cutoff682.25
Noise Cutoff621.15
Domain Noise Cutoff621.15
Isology Typeequivalog
EC Number2.2.1.1
HMM Length654
Mainrole CategoryEnergy metabolism
Subrole CategoryPentose phosphate pathway
Gene Ontology TermGO:0004802: transketolase activity molecular_function
GO:0005737: cytoplasm cellular_component
GO:0006098: pentose-phosphate shunt biological_process
AuthorHaft DH, Richardson DL
Entry DateApr 20 1999 2:10PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis HMM is designed to capture orthologs of bacterial transketolases. The group includes two from the yeast Saccharomyces cerevisiae but excludes dihydroxyactetone synthases (formaldehyde transketolases) from various yeasts and the even more distant mammalian transketolases. Among the family of thiamine diphosphate-dependent enzymes that includes transketolases, dihydroxyacetone synthases, pyruvate dehydrogenase E1-beta subunits, and deoxyxylulose-5-phosphate synthases, mammalian and bacterial transketolases seem not to be orthologous.
ReferencesA2 hmmalign SE TIGR GA hmmls AL clustalw BD 0271
Genome PropertyGenProp0120: pentose phosphate cycle (HMM)