| Accession | TIGR00222 |
| Name | panB |
| Function | 3-methyl-2-oxobutanoate hydroxymethyltransferase |
| Gene Symbol | panB |
| Trusted Cutoff | 207.55 |
| Domain Trusted Cutoff | 207.55 |
| Noise Cutoff | 96.90 |
| Domain Noise Cutoff | 96.90 |
| Isology Type | equivalog |
| EC Number | 2.1.2.11 |
| HMM Length | 264 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Pantothenate and coenzyme A |
| Gene Ontology Term | GO:0003864: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity molecular_function |
| | GO:0015940: pantothenate biosynthetic process biological_process |
| Author | Loftus BJ |
| Entry Date | Apr 20 1999 2:09PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this family are 3-methyl-2-oxobutanoate hydroxymethyltransferase, the first enzyme of the pantothenate biosynthesis pathway. An alternate name is ketopantoate hydroxymethyltransferase. |
| References | SE TIGR
RN [1]
RM 93209959
RT Cloning and sequencing of the Escherichia coli panB gene, which encodes ketopantoate hydroxymethyltransferase, and overexpression of the enzyme.
RA Jones CE, Brook JM, Buck D, Abell C, Smith AG.
RL J Bacteriol. 1993 Apr;175(7):2125-30.
DR ECOCYC; EG11675; panB
DR HAMAP; MF_00156; 403 of 405 |
| Genome Property | GenProp0124: pantothenate biosynthesis from aspartate and 2-oxoisovalerate (HMM) |
