HMM Summary Page: TIGR00199

Functionamidohydrolase, PncC family
Trusted Cutoff68.90
Domain Trusted Cutoff68.90
Noise Cutoff48.95
Domain Noise Cutoff48.95
Isology Typesubfamily_domain
EC Number3.5.-.-
HMM Length149
Mainrole CategoryDNA metabolism
Subrole CategoryDNA replication, recombination, and repair
AuthorLoftus BJ, Haft DH
Entry DateApr 20 1999 2:06PM
Last ModifiedFeb 14 2011 3:27PM
CommentCinA is a DNA damage- or competence-inducible protein that is polycistronic with recA in a number of species. Several bacterial species have a protein consisting largely of the C-terminal domain of CinA but lacking the N-terminal domain, including nicotinamide mononucleotide (NMN) deamidase ( proteins PncC in Shewanella oneidensis and ygaD in E. coli.
ReferencesDR INTERPRO; IPR003396 DR PFAM; PF02464; CinA SE TIGR DR HAMAP; MF_00226; 160 of 185 RN [1] RM PMID:21953451 RT Identification of nicotinamide mononucleotide deamidase of the bacterial pyridine nucleotide cycle reveals a novel broadly conserved amidohydrolase family. RA Galeazzi L, Bocci P, Amici A, Brunetti L, Ruggieri S, Romine M, Reed S, Osterman AL, Rodionov DA, Sorci L, Raffaelli N RL J Biol Chem. 2011 Nov 18;286(46):40365-75.