| Accession | TIGR00198 |
| Name | cat_per_HPI |
| Function | catalase/peroxidase HPI |
| Gene Symbol | katG |
| Trusted Cutoff | 770.25 |
| Domain Trusted Cutoff | 770.25 |
| Noise Cutoff | 427.70 |
| Domain Noise Cutoff | 427.70 |
| Isology Type | equivalog |
| EC Number | 1.11.1.6 |
| HMM Length | 716 |
| Mainrole Category | Cellular processes |
| Subrole Category | Detoxification |
| Gene Ontology Term | GO:0004096: catalase activity molecular_function |
| | GO:0004601: peroxidase activity molecular_function |
| | GO:0006979: response to oxidative stress biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:06PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | As catalase, this enzyme catalyzes the dismutation of two molecules of hydrogen peroxide to dioxygen and two molecules of water. As a peroxidase, it uses hydrogen peroxide to oxidize donor compounds and produce water.
KatG from E. coli is a homotetramer with two non-covalently associated iron protoheme IX groups per tetramer, but the ortholog from Synechococcus sp. is a homodimer with one protoheme.
Important sites (numbered according to E. coli KatG) include heme ligands His-106 and His-267 and active site Trp-318.
Note that the translation PID:g296476 from accession X71420 from Rhodobacter capsulatus B10 contains extensive frameshift differences from the rest of the orthologous family. |
| References | SE TIGR
GA hmmls
AL clustalw
DR HAMAP; MF_01961; 279 of 304 |
| Genome Property | GenProp0213: Resistance to Reactive Oxygen Species (ROS) (HMM) |
| | GenProp0213: Resistance to Reactive Oxygen Species (ROS) (HMM) |
