| Accession | TIGR00191 |
| Name | thrB |
| Function | homoserine kinase |
| Gene Symbol | thrB |
| Trusted Cutoff | 168.25 |
| Domain Trusted Cutoff | 168.25 |
| Noise Cutoff | 161.15 |
| Domain Noise Cutoff | 161.15 |
| Isology Type | equivalog |
| EC Number | 2.7.1.39 |
| HMM Length | 304 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Aspartate family |
| Gene Ontology Term | GO:0004413: homoserine kinase activity molecular_function |
| | GO:0009088: threonine biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:10PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Homoserine kinase is part of the threonine biosynthetic pathway.
Homoserine kinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.
P.aeruginosa homoserine kinase seems not to be homologous (see PROSITE:PDOC0054)
|
| References | DR PROSITE; PDOC0054;
SE TIGR
GA hmmls
AL clustalw, belvu
DR HAMAP; MF_00384; 228 of 231 |
| Genome Property | GenProp0159: threonine biosynthesis from aspartate semialdehyde (HMM) |
