HMM Summary Page: TIGR00185
Accession | TIGR00185 |
Name | tRNA_yibK_trmL |
Function | tRNA (cytidine(34)-2'-O)-methyltransferase |
Gene Symbol | trmL |
Trusted Cutoff | 190.60 |
Domain Trusted Cutoff | 190.60 |
Noise Cutoff | 88.85 |
Domain Noise Cutoff | 88.85 |
Isology Type | equivalog |
EC Number | 2.1.1.207 |
HMM Length | 154 |
Mainrole Category | Protein synthesis |
Subrole Category | tRNA and rRNA base modification |
Gene Ontology Term | GO:0008173: RNA methyltransferase activity molecular_function |
GO:0009451: RNA modification biological_process | |
Author | Richardson DL, Haft DH |
Entry Date | Apr 20 1999 2:09PM |
Last Modified | Dec 8 2011 10:04AM |
Comment | TrmL (previously YibK) is responsible for 2'-O-methylation at tRNA(Leu) position 34. |
References | RN [1] RM PMID:20855540 RT YibK is the 2'-O-methyltransferase TrmL that modifies the wobble nucleotide in Escherichia coli tRNA(Leu) isoacceptors. RA Benitez-Paez A, Villarroya M, Douthwaite S, Gabaldon T, Armengod ME RL RNA. 2010 Nov;16(11):2131-43. RN [2] RM PMID:12596263 RT Structure of the YibK methyltransferase from Haemophilus influenzae (HI0766): a cofactor bound at a site formed by a knot. RA Lim K, Zhang H, Tempczyk A, Krajewski W, Bonander N, Toedt J, Howard A, Eisenstein E, Herzberg O RL Proteins. 2003 Apr 1;51(1):56-67. |