HMM Summary Page: TIGR00177

Functionmolybdenum cofactor synthesis domain
Trusted Cutoff85.35
Domain Trusted Cutoff85.35
Noise Cutoff56.30
Domain Noise Cutoff56.30
Isology Typedomain
HMM Length148
Gene Ontology TermGO:0003824: catalytic activity molecular_function
GO:0006777: Mo-molybdopterin cofactor biosynthetic process biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:08PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe Drosophila protein cinnamon, the Arabidopsis protein cnx1, and rat protein gephyrin each have one domain like MoeA and one like MoaB and Mog. These domains are, however, distantly related to each other, as captured by this HMM. Gephyrin is unusual in that it seems to be a tubulin-binding neuroprotein involved in the clustering of both blycine receptors and GABA receptors, rather than a protein of molybdenum cofactor biosynthesis.
ReferencesSE TIGR GA hmmls AL PSI-BLAST, seaview DR HAMAP; MF_00226; 27 of 185