HMM Summary Page: TIGR00163

Functionphosphatidylserine decarboxylase
Gene Symbolpsd
Trusted Cutoff111.75
Domain Trusted Cutoff111.75
Noise Cutoff53.25
Domain Noise Cutoff53.25
Isology Typeequivalog
EC Number4.1.1.65
HMM Length243
Mainrole CategoryFatty acid and phospholipid metabolism
Subrole CategoryBiosynthesis
Gene Ontology TermGO:0004609: phosphatidylserine decarboxylase activity molecular_function
GO:0008654: phospholipid biosynthetic process biological_process
AuthorHaft DH
Entry DateApr 20 1999 2:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentPhosphatidylserine decarboxylase is synthesized as a single chain precursor. Generation of the pyruvoyl active site from a Ser is coupled to cleavage of a Gly-Ser bond between the larger (beta) and smaller (alpha chains). It is an integral membrane protein. A closely related family, possibly also active as phosphatidylserine decarboxylase, falls under model TIGR00164.
ReferencesRM 98036105 RT Phosphatidylserine decarboxylase. RA Voelker DR RL Biochim Biophys Acta 1997 Sep 4;1348(1-2):236-44 SE TIGR GA hmmls DR InterPro; IPR003817; PS_Dcarbxylase DR PFAM; PF02666; PS_Dcarbxylase DR HAMAP; MF_00663; 22 of 23