HMM Summary Page: TIGR00157
Accession | TIGR00157 |
Name | TIGR00157 |
Function | ribosome small subunit-dependent GTPase A |
Gene Symbol | rsgA |
Trusted Cutoff | 100.00 |
Domain Trusted Cutoff | 100.00 |
Noise Cutoff | 60.00 |
Domain Noise Cutoff | 60.00 |
Isology Type | equivalog |
EC Number | 3.6.-.- |
HMM Length | 247 |
Mainrole Category | Protein synthesis |
Subrole Category | Translation factors |
Gene Ontology Term | GO:0005525: GTP binding molecular_function |
GO:0006412: translation biological_process | |
GO:0043022: ribosome binding molecular_function | |
Author | Haft DH |
Entry Date | Apr 20 1999 2:05PM |
Last Modified | Feb 14 2011 3:27PM |
Comment | Members of this protein were designated YjeQ and are now designated RsgA (ribosome small subunit-dependent GTPase A). The strongest motif in the alignment of these proteins is GXSGVGKS[ST], a classic P-loop for nucleotide binding. This protein has been shown to cleave GTP and remain bound to GDP. A role as a regulator of translation has been suggested. The Aquifex aeolicus ortholog is split into consecutive open reading frames. Consequently, this model was build in fragment mode (-f option). |
References | RN [1] RM 12220175 RT YjeQ, an essential, conserved, uncharacterized protein from Escherichia coli, is an unusual GTPase with circularly permuted G-motifs and marked burst kinetics. RA Daigle DM, Rossi L, Berghuis AM, Aravind L, Koonin EV, Brown ED. RL Biochemistry 2002 Sep 17;41(37):11109-17 RN [2] RM 14973029 RT Studies of the interaction of Escherichia coli YjeQ with the ribosome in vitro. RA Daigle DM, Brown ED. RL J Bacteriol. 2004 Mar;186(5):1381-7. RN [3] RM 15466596 RT A novel GTPase activated by the small subunit of ribosome. RA Himeno H, Hanawa-Suetsugu K, Kimura T, Takagi K, Sugiyama W, Shirata S, Mikami T, Odagiri F, Osanai Y, Watanabe D, Goto S, Kalachnyuk L, Ushida C, Muto A. RL Nucleic Acids Res. 2004 Oct 05;32(17):5303-9. DR HAMAP; MF_01820; 94 of 102 |
Genome Property | GenProp0802: ribosome biogenesis proteins, bacteria (HMM) |