| Accession | TIGR00151 |
| Name | ispF |
| Function | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase |
| Gene Symbol | ispF |
| Trusted Cutoff | 116.45 |
| Domain Trusted Cutoff | 116.45 |
| Noise Cutoff | 42.35 |
| Domain Noise Cutoff | 42.35 |
| Isology Type | equivalog_domain |
| EC Number | 4.6.1.12 |
| HMM Length | 155 |
| Mainrole Category | Biosynthesis of cofactors, prosthetic groups, and carriers |
| Subrole Category | Other |
| Gene Ontology Term | GO:0008685: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity molecular_function |
| | GO:0019288: isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway biological_process |
| Author | Haft DH, Richardson DL |
| Entry Date | Apr 20 1999 2:05PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | Members of this protein family are 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, the IspF protein of the deoxyxylulose (non-mevalonate) pathway of IPP biosynthesis. This protein occurs as an IspDF bifunctional fusion protein in about 20 percent of bacterial genomes. |
| References | SE TIGR
AL msa
DR SWISS-PROT; P36663; annotated E. coli entry
DR HAMAP; MF_01520; 79 of 79 |
| Genome Property | GenProp0048: IPP biosynthesis via deoxyxylulose (HMM) |
