HMM Summary Page: TIGR00148

Functiondecarboxylase, UbiD family
Trusted Cutoff244.85
Domain Trusted Cutoff244.85
Noise Cutoff15.90
Domain Noise Cutoff15.90
Isology Typesubfamily
EC Number4.1.1.-
HMM Length438
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0016831: carboxy-lyase activity molecular_function
AuthorHaft DH
Entry DateApr 20 1999 2:05PM
Last ModifiedFeb 21 2012 12:15PM
CommentThe member of this family in E. coli is UbiD, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase. The family described by this HMM, however, is broad enough that it is likely to contain several different decarboxylases. Found in bacteria, archaea, and yeast, with two members in A. fulgidus. No homologs were detected besides those classified as orthologs. The member from H. pylori has a C-terminal extension of just over 100 residues that is shared in part by the Aquifex aeolicus homolog.
ReferencesSE TIGR RN [1] RM 11029449 RT Identification of the ubiD gene on the Escherichia coli chromosome. RA Zhang H, Javor GT. RL J Bacteriol. 2000 Nov;182(21):6243-6. RN [2] RM 12799002 RT Regulation of the isofunctional genes ubiD and ubiX of the ubiquinone biosynthetic pathway of Escherichia coli. RA Zhang H, Javor GT. RL FEMS Microbiol Lett. 2003 Jun 6;223(1):67-72. DR HAMAP; MF_01636; 114 of 117