| Accession | TIGR00143 |
| Name | hypF |
| Function | carbamoyltransferase HypF |
| Gene Symbol | hypF |
| Trusted Cutoff | 466.10 |
| Domain Trusted Cutoff | 466.10 |
| Noise Cutoff | 359.80 |
| Domain Noise Cutoff | 359.80 |
| Isology Type | equivalog |
| HMM Length | 741 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein modification and repair |
| Gene Ontology Term | GO:0003998: acylphosphatase activity molecular_function |
| | GO:0006464: protein modification process biological_process |
| Author | Haft DH, Richardson DL |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | A previously described regulatory effect of HypF mutatation is attributable to loss of activity of a regulatory hydrogenase. A zinc finger-like region CXXCX(18)CXXCX(24)CXXCX(18)CXXC region further supported the regulatory hypothesis. However, more recent work (PUBMED:11375153) shows the direct effect is on the activity of expressed hydrogenases with nickel/iron centers, rather than on expression. |
| References | RM 11375153
RT Transposon mutagenesis in purple sulfur photosynthetic bacteria: identification of hypF, encoding a protein capable of processing [NiFe] hydrogenases in alpha, beta, and gamma subdivisions of the proteobacteria.
RA Fodor B, Rakhely G, Kovacs AT, Kovacs KL.
RL Appl Environ Microbiol 2001 Jun;67(6):2476-83 |
| Genome Property | GenProp0177: nickel-dependent hydrogenase (HMM) |
