| Accession | TIGR00138 |
| Name | rsmG_gidB |
| Function | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG |
| Gene Symbol | rsmG |
| Trusted Cutoff | 99.50 |
| Domain Trusted Cutoff | 99.50 |
| Noise Cutoff | 75.90 |
| Domain Noise Cutoff | 75.90 |
| Isology Type | equivalog |
| EC Number | 2.1.1.170 |
| HMM Length | 183 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0005575: cellular_component cellular_component |
| | GO:0008168: methyltransferase activity molecular_function |
| | GO:0031167: rRNA methylation biological_process |
| | GO:0046118: 7-methylguanosine biosynthetic process biological_process |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | RsmG was previously called GidB (glucose-inhibited division protein B). It is present and a single copy in nearly all complete eubacterial genomes. It is missing only from some obligate intracellular species of various lineages (Chlamydiae, Ehrlichia, Wolbachia, Anaplasma, Buchnera, etc.). RsmG shows a methytransferase fold in its the crystal structure, and acts as a 7-methylguanosine (m(7)G) methyltransferase, apparently specific to 16S rRNA. |
| References | RN [1]
RM PMID:17238915
RT Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance in bacteria.
RA Okamoto S, Tamaru A, Nakajima C, Nishimura K, Tanaka Y, Tokuyama S, Suzuki Y, Ochi K
RN [2]
RM 12001236
RT Crystal structure of the Escherichia coli glucose-inhibited division protein B (GidB) reveals a methyltransferase fold.
RA Romanowski MJ, Bonanno JB, Burley SK.
RL Proteins. 2002 Jun 1;47(4):563-7.
DR HAMAP; MF_00074; 519 of 539 |
| Genome Property | GenProp0802: ribosome biogenesis proteins, bacteria (HMM) |
