| Accession | TIGR00136 |
| Name | gidA |
| Function | tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA |
| Gene Symbol | gidA |
| Trusted Cutoff | 524.85 |
| Domain Trusted Cutoff | 524.85 |
| Noise Cutoff | 97.00 |
| Domain Noise Cutoff | 97.00 |
| Isology Type | equivalog |
| HMM Length | 616 |
| Mainrole Category | Protein synthesis |
| Subrole Category | tRNA and rRNA base modification |
| Gene Ontology Term | GO:0006400: tRNA modification biological_process |
| | GO:0016740: transferase activity molecular_function |
| Author | Haft DH |
| Entry Date | Apr 20 1999 2:07PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | GidA, the longer of two forms of GidA-related proteins, appears to be present in all complete eubacterial genomes so far, as well as Saccharomyces cerevisiae. A subset of these organisms have a closely related protein. GidA is absent in the Archaea. It appears to act with MnmE, in an alpha2/beta2 heterotetramer, in the 5-carboxymethylaminomethyl modification of uridine 34 in certain tRNAs. The shorter, related protein, previously called gid or gidA(S), is now called TrmFO (see model TIGR00137). |
| References | RN [1]
RM PMID: 17062623
RT Further insights into the tRNA modification process controlled by proteins MnmE and GidA of Escherichia coli.
RA Yim L, Moukadiri I, Bjork GR, Armengod ME
RL Nucleic Acids Res. 2006;34(20):5892-905.
DR HAMAP; MF_00129; 524 of 540 |
| Genome Property | GenProp0704: tRNA U34 carboxymethylaminomethyl modification (HMM) |
