HMM Summary Page: TIGR00133

Functionaspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit
Gene SymbolgatB
Trusted Cutoff314.80
Domain Trusted Cutoff314.80
Noise Cutoff199.15
Domain Noise Cutoff199.15
Isology Typeequivalog
EC Number6.3.5.-
HMM Length481
Mainrole CategoryProtein synthesis
Subrole CategorytRNA aminoacylation
Gene Ontology TermGO:0006424: glutamyl-tRNA aminoacylation biological_process
GO:0030956: glutamyl-tRNA(Gln) amidotransferase complex cellular_component
GO:0050567: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity molecular_function
AuthorHaft DH
Entry DateApr 20 1999 2:07PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe heterotrimer GatABC is responsible for transferring the NH2 group that converts Glu to Gln, or Asp to Asn after the Glu or Asp has been ligated to the tRNA for Gln or Asn, respectively. In Lactobacillus, GatABC is responsible only for tRNA(Gln). In the Archaea, GatABC is responsible only for tRNA(Asn), while GatDE is responsible for tRNA(Gln). In lineages that include Thermus, Chlamydia, or Acidithiobacillus, the GatABC complex catalyzes both.
ReferencesRL Proc Natl Acad Sci U S A. 94, 11819-11826, 1997; RL J Bacteriol 179, 5625-5627, 1997; RL Curr Genet 25, 299-304, 1994 SE TIGR GA hmmls AL clustalw DR HAMAP; MF_00121; 407 of 409
Genome PropertyGenProp0188: GatABC aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase complex (HMM)
GenProp0258: tRNA aminoacylation (HMM)
GenProp0258: tRNA aminoacylation (HMM)