| Accession | TIGR00110 |
| Name | ilvD |
| Function | dihydroxy-acid dehydratase |
| Gene Symbol | ilvD |
| Trusted Cutoff | 618.15 |
| Domain Trusted Cutoff | 618.15 |
| Noise Cutoff | 339.10 |
| Domain Noise Cutoff | 339.10 |
| Isology Type | equivalog |
| EC Number | 4.2.1.9 |
| HMM Length | 543 |
| Mainrole Category | Amino acid biosynthesis |
| Subrole Category | Pyruvate family |
| Gene Ontology Term | GO:0004160: dihydroxy-acid dehydratase activity molecular_function |
| | GO:0009097: isoleucine biosynthetic process biological_process |
| | GO:0009099: valine biosynthetic process biological_process |
| Author | Anolik RT, Richardson DL, Haft DH |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | This protein, dihydroxy-acid dehydratase, catalyzes the fourth step in valine and isoleucine biosynthesis. It contains a catalytically essential [4Fe-4S] cluster
This model generates scores of up to 150 bits vs. 6-phosphogluconate dehydratase, a homologous enzyme. |
| References | DR PROSITE: PDOC00690
SE TIGR
GA hmmls
DR HAMAP; MF_00012; 409 of 418 |
| Genome Property | GenProp0162: isoleucine biosynthesis from threonine and pyruvate (HMM) |
| | GenProp0163: valine biosynthesis from pyruvate (HMM) |
| | GenProp0164: leucine biosynthesis from pyruvate and acetyl-CoA (HMM) |
