HMM Summary Page: TIGR00103

FunctionDNA-binding protein, YbaB/EbfC family
Trusted Cutoff49.45
Domain Trusted Cutoff49.45
Noise Cutoff47.85
Domain Noise Cutoff47.85
Isology Typeequivalog
HMM Length104
Mainrole CategoryUnknown function
Subrole CategoryGeneral
Gene Ontology TermGO:0003677: DNA binding molecular_function
GO:0005737: cytoplasm cellular_component
GO:0008150: biological_process biological_process
AuthorAnolik RT, Richardson DL, Haft DH
Entry DateApr 20 1999 2:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentThe function of this protein is unknown, but it has been expressed and crystallized. Its gene nearly always occurs next to recR and/or dnaX. It is restricted to Bacteria and the plant Arabidopsis. The plant form contains an additional N-terminal region that may serve as a transit peptide and shows a close relationship to the cyanobacterial member, suggesting that it is a chloroplast protein. Members of this family are found in a single copy per bacterial genome, but are broadly distributed. A member is present even in the minimal gene complement of Mycoplasm genitalium.
ReferencesRN [1] RM PMID:19594923 RT DNA-binding by Haemophilus influenzae and Escherichia coli YbaB, members of a widely-distributed bacterial protein family. RA Cooley AE, Riley SP, Kral K, Miller MC, DeMoll E, Fried MG, Stevenson B RL BMC Microbiol. 2009 Jul 13;9:137. RN [2] RM PMID: 12486730 RT Crystal structure of YbaB from Haemophilus influenzae (HI0442), a protein of unknown function coexpressed with the recombinational DNA repair protein RecR. RA Lim K, Tempczyk A, Parsons JF, Bonander N, Toedt J, Kelman Z, Howard A, Eisenstein E, Herzberg O RL Proteins. 2003 Feb 1;50(2):375-9. RN [3] RM PMID:16740939 RT Borrelia burgdorferi EbfC, a novel, chromosomally encoded protein, binds specific DNA sequences adjacent to erp loci on the spirochete's resident cp32 prophages. RA Babb K, Bykowski T, Riley SP, Miller MC, Demoll E, Stevenson B RL J Bacteriol. 2006 Jun;188(12):4331-9. DR HAMAP; MF_00274; 377 of 383