| Accession | TIGR00100 |
| Name | hypA |
| Function | hydrogenase nickel insertion protein HypA |
| Gene Symbol | hypA |
| Trusted Cutoff | 88.10 |
| Domain Trusted Cutoff | 88.10 |
| Noise Cutoff | 56.80 |
| Domain Noise Cutoff | 56.80 |
| Isology Type | equivalog |
| HMM Length | 116 |
| Mainrole Category | Protein fate |
| Subrole Category | Protein modification and repair |
| Gene Ontology Term | GO:0006464: protein modification process biological_process |
| | GO:0008901: ferredoxin hydrogenase activity molecular_function |
| Author | Haft DH, Anolik RT |
| Entry Date | Apr 20 1999 2:08PM |
| Last Modified | Feb 14 2011 3:27PM |
| Comment | CXXC-~12X-CXXC and genetically seems a regulatory protein.
In Hpylori, hypA mutant abolished hydrogenase activity and decrease in urease activity. Nickel supplementation in media restored urease activity and partial hydrogenase activity. HypA probably involved in inserting Ni in enzymes. |
| References | SE TIGR
RM 12081959
RT Network of hydrogenase maturation in Escherichia coli: role of accessory proteins HypA and HybF.
RA Hube M, Blokesch M, Bock A.
RL J Bacteriol 2002 Jul;184(14):3879-85
DR HAMAP; MF_00213; 97 of 111 |
