HMM Summary Page: TIGR00082

Functionribosome-binding factor A
Gene SymbolrbfA
Trusted Cutoff51.15
Domain Trusted Cutoff51.15
Noise Cutoff40.60
Domain Noise Cutoff40.60
Isology Typeequivalog
HMM Length115
Mainrole CategoryTranscription
Subrole CategoryRNA processing
Gene Ontology TermGO:0006396: RNA processing biological_process
GO:0019843: rRNA binding molecular_function
AuthorRichardson DL
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentAssociates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'terminal helix region of 16S rRNA. Mutants lacking rbfA have a cold-sensitive phenotype.
ReferencesRN [1] RT Suppression of a cold-sensitive mutation in 16S rRNA by overexpression of a novel ribosome-binding factor, RbfA. RA Dammel CS, Noller HF RL Genes Dev 1995 Mar 1;9(5):626-37 RN [2] RM 98083058 RT RimM and RbfA are essential for efficient processing of 16S rRNA in Escherichia coli. RA Bylund GO, Wipemo LC, Lundberg LA, Wikstrom PM RL J Bacteriol 1998 Jan;180(1):73-82 DR Genes Dev 1995 Mar 1;9(5):626-637 SE TIGR GA hmmls AL msa DR HAMAP; MF_00003; 492 of 510
Genome PropertyGenProp0799: bacterial core gene set, exactly 1 per genome (HMM)