HMM Summary Page: TIGR00058

Functionhemerythrin family non-heme iron protein
Trusted Cutoff131.85
Domain Trusted Cutoff131.85
Noise Cutoff70.80
Domain Noise Cutoff70.80
Isology Typesubfamily
HMM Length115
AuthorRichardson DL, Haft DH
Entry DateApr 20 1999 2:03PM
Last ModifiedFeb 21 2012 12:28PM
CommentThis family includes oxygen carrier proteins of various oligomeric states from the vascular fluid (hemerythrin) and muscle (myohemerythrin) of some marine invertebrates. Each unit binds 2 non-heme Fe using 5 H, one E and one D. One member of this family,from the sandworm Nereis diversicolor, is an unusual (non-metallothionein) cadmium-binding protein. Homologous proteins, excluded from this narrowly defined family, are found in archaea and bacteria (see PF01814).
ReferencesA2 hmmalign DR PROSITE; PDOC00476; hemerythrins DR PFAM; PF01814; Hemerythrin SE TIGR AL clustalw