HMM Summary Page: TIGR00055

Gene SymboluppS
Trusted Cutoff109.55
Domain Trusted Cutoff109.55
Noise Cutoff25.10
Domain Noise Cutoff25.10
Isology Typeequivalog
EC Number2.5.1.31
HMM Length228
Mainrole CategoryCell envelope
Subrole CategoryBiosynthesis and degradation of surface polysaccharides and lipopolysaccharides
Gene Ontology TermGO:0005737: cytoplasm cellular_component
GO:0008834: di-trans,poly-cis-decaprenylcistransferase activity molecular_function
GO:0009252: peptidoglycan biosynthetic process biological_process
AuthorRichardson DL, Haft DH
Entry DateApr 20 1999 2:04PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae.
ReferencesRN [1] RM 98344035 RT Molecular cloning, expression, and purification of undecaprenyl diphosphate synthase. No sequence similarity between E- and Z-prenyl diphosphate synthases. RA Shimizu N, Koyama T, Ogura K RL J Biol Chem 1998 Jul 31;273(31):19476-81 RN [2] RM 99102211 RT Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene. RA Apfel CM, Takacs B, Fountoulakis M, Stieger M, Keck W RL J Bacteriol 1999 Jan;181(2):483-92 SE TIGR AL msa DR HAMAP; MF_01139; 186 of 187
Genome PropertyGenProp0971: biosynthesis of undecaprenyl phosphate (Und-P) (HMM)