HMM Summary Page: TIGR00050

FunctionRNA methyltransferase, TrmH family, group 1
Trusted Cutoff167.15
Domain Trusted Cutoff167.15
Noise Cutoff89.40
Domain Noise Cutoff89.40
Isology Typesubfamily
EC Number2.1.1.-
HMM Length233
Mainrole CategoryProtein synthesis
Subrole CategorytRNA and rRNA base modification
Gene Ontology TermGO:0008173: RNA methyltransferase activity molecular_function
GO:0009451: RNA modification biological_process
AuthorRichardson DL, Haft DH
Entry DateApr 20 1999 2:09PM
Last ModifiedFeb 14 2011 3:27PM
CommentThis is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen
ReferencesSE TIGR RN [1] RM PMID: 16848900 RT The yfhQ gene of Escherichia coli encodes a tRNA:Cm32/Um32 methyltransferase. RA Purta E, van Vliet F, Tkaczuk KL, Dunin-Horkawicz S, Mori H, Droogmans L, Bujnicki JM RL BMC Mol Biol. 2006 Jul 18;7(1):23. RN [2] RM 94089409 RT SpoU protein of Escherichia coli belongs to a new family of putative rRNA methylases. RA Koonin EV, Rudd KE RL Nucleic Acids Res 1993 Nov 25;21(23):5519